A mechanical model reveals that non-axisymmetric buckling lowers the energy barrier associated with membrane neck constriction

Author:

Vasan R.1234ORCID,Rudraraju S.5674,Akamatsu M.89104,Garikipati K.111213144ORCID,Rangamani P.1234ORCID

Affiliation:

1. Department of Mechanical and Aerospace Engineering

2. University of California San Diego

3. La Jolla

4. USA

5. Department of Mechanical Engineering

6. University of Wisconsin-Madison

7. Madison

8. Department of Molecular and Cell Biology

9. University of California

10. Berkeley

11. Departments of Mechanical Engineering and Mathematics

12. Michigan Institute for Computational Discovery & Engineering

13. University of Michigan

14. Ann Arbor

Abstract

Using computational modeling, we show that membrane neck formation, which is essential for scission can be both location and symmetry dependent.

Funder

Army Research Office

Wisconsin Alumni Research Foundation

Division of Materials Research

Office of Naval Research

Publisher

Royal Society of Chemistry (RSC)

Subject

Condensed Matter Physics,General Chemistry

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