An antibody scanning method for the detection of α-synuclein oligomers in the serum of Parkinson's disease patients-Reference-Cited by-同舟云学术

An antibody scanning method for the detection of α-synuclein oligomers in the serum of Parkinson's disease patients

Published:2022 Issue:46 Volume:13 Page:13815-13828
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Kulenkampff Klara¹^ORCID,Emin Derya²³,Staats Roxine¹,Zhang Yu P.²,Sakhnini Laila¹,Kouli Antonina⁴,Rimon Oded¹^ORCID,Lobanova Evgeniia²³,Williams-Gray Caroline H.⁴,Aprile Francesco A.¹,Sormanni Pietro¹,Klenerman David²³,Vendruscolo Michele¹^ORCID

Affiliation:

1. Centre for Misfolding Diseases, Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge CB2 1EW, UK

2. Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge, CB2 1EW, UK

3. UK Dementia Research Institute, University of Cambridge, Cambridge, CB2 0XY, UK

4. John Van Geest Centre for Brain Repair, Department of Clinical Neurosciences, University of Cambridge, UK

Abstract

Misfolded α-synuclein oligomers are closely implicated in the pathology of Parkinson's disease and related synucleinopathies.

Funder

Medical Research Council

Royal Society

Cambridge Centre for Parkinson-Plus

Parkinson's UK

UK Dementia Research Institute

European Research Council

NIHR Cambridge Biomedical Research Centre

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/SC/D2SC00066K

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2. Global, regional, and national burden of neurological disorders, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016

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4. Targeting Alpha-Synuclein as a Therapy for Parkinson’s Disease

5. Parkinson’s Disease Drug Therapies in the Clinical Trial Pipeline: 2020

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