Hypoxia-specific anti-RAGE exosomes for nose-to-brain delivery of anti-miR-181a oligonucleotide in an ischemic stroke model-Reference-Cited by-同舟云学术

Hypoxia-specific anti-RAGE exosomes for nose-to-brain delivery of anti-miR-181a oligonucleotide in an ischemic stroke model

Published:2021 Issue:33 Volume:13 Page:14166-14178
ISSN:2040-3364
Container-title:Nanoscale
language:en
Short-container-title:Nanoscale

Author:

Kim Minkyung¹,Lee Youngki¹,Lee Minhyung¹^ORCID

Affiliation:

1. Department of Bioengineering, College of Engineering, Hanyang University, 222 Wangsimni-ro, Seondong-gu, Seoul 04763, Korea

Abstract

An exosome linked to RAGE-binding-peptide was developed as a hypoxia-specific carrier for nose-to-brain delivery of anti-microRNA oligonucleotide for ischemic stroke therapy.

Funder

National Research Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

Link

http://pubs.rsc.org/en/content/articlepdf/2021/NR/D0NR07516G

Reference51 articles.

1. Tissue Plasminogen Activator for Acute Ischemic Stroke

2. Can Restoring Incomplete Microcirculatory Reperfusion Improve Stroke Outcome after Thrombolysis?

3. A self-assembled DNA-nanoparticle with a targeting peptide for hypoxia-inducible gene therapy of ischemic stroke

4. Therapeutic effects of a reducible poly (oligo-d-arginine) carrier with the heme oxygenase-1 gene in the treatment of hypoxic-ischemic brain injury

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