Lactiplantibacillus plantarum 22A-3-induced TGF-β1 secretion from intestinal epithelial cells stimulated CD103+ DC and Foxp3+ Treg differentiation and amelioration of colitis in mice-Reference-Cited by-同舟云学术

Lactiplantibacillus plantarum 22A-3-induced TGF-β1 secretion from intestinal epithelial cells stimulated CD103+ DC and Foxp3+ Treg differentiation and amelioration of colitis in mice

Published:2021 Issue:17 Volume:12 Page:8044-8055
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Lamubol Jarukan¹,Ohto Nobuaki²,Kuwahara Hiroshige²,Mizuno Masashi¹^ORCID

Affiliation:

1. Department of Agrobioscience, Graduate School of Agricultural Science, Kobe University, Kobe 657-8501, Japan

2. Maruzen Pharmaceuticals Co. Ltd, Fukuyama, Hiroshima 722-0062, Japan

Abstract

LP22A3 induced TGF-β1 secretion from IECs of the small intestine through TLR2, and resulted in the promotion of Foxp3+ Treg and CD103+ DC population, which secreted anti-inflammatory cytokines providing a protective condition in the intestine.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

Link

http://pubs.rsc.org/en/content/articlepdf/2021/FO/D1FO00990G

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