Oxidative radical cascade cyclization involving C(sp3)–C(sp3), C(sp3)–C(sp2) and C(sp2)–N bonds formation: direct construction of cyano and methyl substituted polyheterocycles

Author:

Shang Jia-Qi1234,Wang Shi-Sheng1234,Fu Hong1234,Li Yi1234,Yang Tao1234,Li Ya-Min1234ORCID

Affiliation:

1. Faculty of Life Science and Technology

2. Kunming University of Science and Technology

3. Kunming 650500

4. P. R. China

Abstract

Oxidative radical cascade cyclizations of 2-cyano-3-arylaniline derived acrylamides with acetonitrile and tert-butyl peroxybenzoate have been developed to construct cyano and methyl substituted pyrido[4,3,2-gh]phenanthridines.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Reference68 articles.

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2. Natural Products in Medicinal Chemistry , ed. S. Hanessian , Wiley-VCH , Weinheim , 2014

3. Big Is Beautiful−“Aromaticity” Revisited from the Viewpoint of Macromolecular and Supramolecular Benzene Chemistry

4. The electroluminescence of organic materials

5. The Larger Acenes: Versatile Organic Semiconductors

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