Photoinduced tandem radical cyclization/heteroarylation of <i>N</i>-allylbromodifluoroacetamides with quinoxalin-2(1<i>H</i>)-ones or coumarins under metal- and photocatalyst-free conditions-Reference-Cited by-同舟云学术

Photoinduced tandem radical cyclization/heteroarylation of N-allylbromodifluoroacetamides with quinoxalin-2(1H)-ones or coumarins under metal- and photocatalyst-free conditions

Published:2023 Issue:22 Volume:47 Page:10744-10750
ISSN:1144-0546
Container-title:New Journal of Chemistry
language:en
Short-container-title:New J. Chem.

Author:

Zhao Wei¹,Xuan Liangming¹,Liu Yang¹,Yin Jiayi¹,Wang Haifeng¹,Yan Qiongjiao¹,Wang Wei¹^ORCID,Huang Jin²,Chen Fener¹³⁴^ORCID

Affiliation:

1. Pharmaceutical Research Institute, Wuhan Institute of Technology, Wuhan 430205, P. R. China

2. The College of Post and Telecommunication of WIT, Wuhan 430073, P. R. China

3. Engineering Center of Catalysis and Synthesis for Chiral Molecules, Department of Chemistry, Fudan University, Shanghai 200433, P. R. China

4. Shanghai Engineering Center of Industrial Catalysis for Chiral Drugs, Shanghai 200433, P. R. China

Abstract

A photocatalyst-free visible-light-promoted tandem intramolecular cyclization/heteroarylation between bromodifluoroacetamides and quinoxalin-2(1H)-ones or coumarins was developed. The process could generate a broad range of α,α-difluoro-γ-lactams.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2023/NJ/D3NJ01329D

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