Preactivation-based, iterative one-pot synthesis of anticoagulant pentasaccharide fondaparinux sodium-Reference-Cited by-同舟云学术

Preactivation-based, iterative one-pot synthesis of anticoagulant pentasaccharide fondaparinux sodium

Published:2019 Issue:17 Volume:6 Page:3116-3120
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Jin Hongzhen¹²³⁴⁵,Chen Qiang¹²³⁴⁵,Zhang Yan-Yan¹²³⁴⁵,Hao Kai-Feng¹²³⁴⁵,Zhang Guo-Qiang¹²³⁴⁵,Zhao Wei¹²³⁴⁵^ORCID

Affiliation:

1. The State Key Laboratory of Medicinal Chemical Biology

2. College of Pharmacy and Tianjin Key Laboratory of Molecular Drug Research

3. Nankai University

4. Tianjin 300353

5. People's Republic of China

Abstract

A one-pot, three-component synthetic strategy was designed to rapidly assemble fondaparinux, using a monosaccharide donor and two disaccharide acceptors.

Funder

National Natural Science Foundation of China

National Basic Research Program of China

Natural Science Foundation of Tianjin City

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/QO/C9QO00480G

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