A new family of luminescent iridium complexes: synthesis, optical, and cytotoxic studies-Reference-Cited by-同舟云学术

A new family of luminescent iridium complexes: synthesis, optical, and cytotoxic studies

Published:2023 Issue:19 Volume:52 Page:6360-6374
ISSN:1477-9226
Container-title:Dalton Transactions
language:en
Short-container-title:Dalton Trans.

Author:

Millán Gonzalo¹,Nieddu Mattia¹²^ORCID,López Icíar P.³,Ezquerro Cintia¹,Berenguer Jesús R.¹^ORCID,Larráyoz Ignacio M.⁴⁵,Pichel José G.³⁶^ORCID,Lalinde Elena¹^ORCID

Affiliation:

1. Departamento de Química-Centro de Síntesis Química de La Rioja, (CISQ), Universidad de La Rioja, 26006, Logroño, Spain

2. Chair of Biogenic Functional Materials, Technical University of Munich, Schulgasse, 22, Straubing 94315, Germany

3. Lung Cancer and Respiratory Diseases Unit (CIBIR), Fundación Rioja Salud, 26006, Logroño, Spain

4. Unidad Predepartamental de Enfermería, Universidad de La Rioja, Duquesa de la Victoria 88, E–26006, Logroño, Spain

5. Biomarkers and Molecular Signaling Unit (CIBIR), Fundación Rioja Salud, 26006, Logroño, Spain

6. Biomedical Research Networking Center in Respiratory Diseases (CIBERES), ISCIII, Spain

Abstract

A new family of luminescent cyclometalated Ir(iii) complexes [Ir(C^N)2(N^N)]+was prepared. The most cytotoxic complex 2a-Cl locates in lysosomes but acts destroying mitochondria, while 3a-PF6 revelled its potential as photosensitiser in PDT.

Funder

Ministerio de Ciencia e Innovación

European Regional Development Fund

Agencia de Desarrollo Económico

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/DT/D3DT00028A

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1. New trends in platinum and palladium complexes as antineoplastic agents