Synthetic ease and exceptional <i>in vivo</i> performance of pyrazole-based cyclometallated iridium complexes-Reference-Cited by-同舟云学术

Synthetic ease and exceptional in vivo performance of pyrazole-based cyclometallated iridium complexes

Published:2024 Issue:6 Volume:11 Page:1828-1838
ISSN:2052-1553
Container-title:Inorganic Chemistry Frontiers
language:en
Short-container-title:Inorg. Chem. Front.

Author:

Redrado Marta¹^ORCID,Romanos Eduardo²,Benedi Andrea³^ORCID,Canudo-Barreras Guillermo¹,Marzo Isabel³,Gimeno M. Concepción¹^ORCID,Fernández-Moreira Vanesa¹^ORCID

Affiliation:

1. Departamento de Química Inorgánica, Instituto de Síntesis Química y Catálisis Homogénea (ISQCH) CSIC-Universidad de Zaragoza, 50009 Zaragoza, Spain

2. Departamento de Imagen y Fenotipado, Instituto Aragonés de Ciencias de la Salud. Centro de Investigación Biomédica de Aragón (CIBA), 50009 Zaragoza, Spain

3. Departamento de Bioquímica y Biología Celular, Universidad de Zaragoza, 50009 Zaragoza, Spain

Abstract

Novel cyclometallated IrIII complexes, exhibiting dual functionality as potent anticancer agents and photosensitisers, with selective efficacy against specific cancer cell lines.

Funder

Agencia Estatal de Investigación

Gobierno de Aragón

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/QI/D3QI02355A

Reference59 articles.

1. Mitochondria-targeted spin-labelled luminescent iridium anticancer complexes

2. The design of cyclometalated iridium(iii)–metformin complexes for hypoxic cancer treatment

3. A new family of luminescent iridium complexes: synthesis, optical, and cytotoxic studies

4. Multifunctional Heterometallic Ir III −Au I Probes as Promising Anticancer and Antiangiogenic Agents

5. Exploring the Phototoxicity of Hypoxic Active Iridium(III)-Based Sensitizers in 3D Tumor Spheroids

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