Structural advances of Siglecs: insight into synthetic glycan ligands for immunomodulation-Reference-Cited by-同舟云学术

Structural advances of Siglecs: insight into synthetic glycan ligands for immunomodulation

Published:2020 Issue:30 Volume:18 Page:5784-5797
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Movsisyan Levon D.¹²³⁴,Macauley Matthew S.¹²³⁴⁵^ORCID

Affiliation:

1. Department of Chemistry

2. University of Alberta

3. Edmonton

4. Canada

5. Department of Medical Microbiology and Immunology

Abstract

This review summarizes the natural and synthetic glycan ligands of Siglecs and the growing body of knowledge for structural features governing sialic acid recognition.

Funder

Natural Sciences and Engineering Research Council of Canada

Canada Research Chairs

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2020/OB/D0OB01116A

Reference145 articles.

1. Siglecs and their roles in the immune system

2. Siglecs: A journey through the evolution of sialic acid-binding immunoglobulin-type lectins

3. Mouse Siglec-F and human Siglec-8 are functionally convergent paralogs that are selectively expressed on eosinophils and recognize 6′-sulfo-sialyl Lewis X as a preferred glycan ligand

4. Immune Inhibitory Receptors

5. CD22 ligand-binding and signaling domains reciprocally regulate B-cell Ca2+ signaling

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