Copper-dependent and -independent hypoxia-inducible factor-1 regulation of gene expression-Reference-Cited by-同舟云学术

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Copper-dependent and -independent hypoxia-inducible factor-1 regulation of gene expression

Published:2014 Issue:10 Volume:6 Page:1889-1893
ISSN:1756-5901
Container-title:Metallomics
language:en
Short-container-title:Metallomics

Author:

Zhang Zhen¹²³⁴⁵,Qiu Liying¹²³⁶⁷,Lin Chen¹²³,Yang Hong¹²³,Fu Haiying¹²³,Li Rui¹²³,Kang Y. James¹²³

Affiliation:

1. Regenerative Medicine Research Center

2. Sichuan University

3. Chengdu, P. R. China

4. State Key Laboratory of Biotherapy

5. West China Hospital

6. College of Chemistry and Environmental Protection Engineering

7. Southwest University for Nationalities

Abstract

HIF-1 mediated expression of BNIP3 by cobalt chloride is Cu-dependent, but the expression of IGF-2 is Cu-independent.

Publisher

Oxford University Press (OUP)

Subject

Metals and Alloys,Biochemistry,Biomaterials,Biophysics,Chemistry (miscellaneous)

Link

http://pubs.rsc.org/en/content/articlepdf/2014/MT/C4MT00052H

Reference24 articles.

1. Effect of desferrioxamine and metals on the hydroxylases in the oxygen sensing pathway

2. Regulation of hypoxia-inducible factor 1 is mediated by an O2-dependent degradation domain via the ubiquitin-proteasome pathway

3. Targeting of HIF-α to the von Hippel-Lindau Ubiquitylation Complex by O 2 -Regulated Prolyl Hydroxylation

4. HIFα Targeted for VHL-Mediated Destruction by Proline Hydroxylation: Implications for O 2 Sensing

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