Regulation of hypoxia-inducible factor 1 is mediated by an O2-dependent degradation domain via the ubiquitin-proteasome pathway
Author:
Publisher
Proceedings of the National Academy of Sciences
Subject
Multidisciplinary
Reference38 articles.
1. Oxygen sensing and molecular adaptation to hypoxia
2. The Hypoxic Response: Huffing and HIFing
3. A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation.
4. Characterization of hypoxia-inducible factor 1 and regulation of DNA binding activity by hypoxia.
5. Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension.
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