A metal-free approach to highly functionalized 3-substituted-3-arylbenzofuran-2(3<i>H</i>)-ones-Reference-Cited by-同舟云学术

A metal-free approach to highly functionalized 3-substituted-3-arylbenzofuran-2(3H)-ones

Published:2022 Issue:45 Volume:46 Page:21906-21910
ISSN:1144-0546
Container-title:New Journal of Chemistry
language:en
Short-container-title:New J. Chem.

Author:

Dhotare Bhaskar B.¹,Kumar Sahil¹,Wadawale Amey²,Nayak Sandip K.¹,Kumar Mukesh³⁴^ORCID,Goswami Dibakar¹⁴^ORCID

Affiliation:

1. Bio-Organic Division, Bhabha Atomic Research Centre, Trombay, Mumbai PIN-400085, India

2. Chemistry Division, Bhabha Atomic Research Centre, Trombay, Mumbai PIN-400085, India

3. Radiation Biology & Health Sciences Division, Bhabha Atomic Research Centre, Trombay, Mumbai PIN-400085, India

4. Homi Bhabha National Institute, Anushaktinagar, Mumbai PIN-400094, India

Abstract

A novel approach for H2SO4-mediated dehydrative substitution of 3-hydroxy-3-phenylbenzofuran-2(3H)-ones with electron-rich arenes/1,3-diones/alcohols/thiols as nucleophiles is presented.

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2022/NJ/D2NJ03404B

Reference34 articles.

1. The synthesis of a natural product family: from debromoisolaurinterol to the aplysins

2. Isoaurostatin: total synthesis and structural revision

3. Metal‐Free Tandem Rearrangement/Lactonization: Access to 3,3‐Disubstituted Benzofuran‐2‐(3 H )‐ones

4. Construction of benzofuranone library via a metal-free, one-pot intermolecular condensation, and their application as efficient estrogen receptor β modulators

5. Asymmetric Rh(I)-Catalyzed Functionalization of the 3-C(sp3)–H Bond of Benzofuranones with α-Diazoesters