Pharmacokinetic, partial pharmacodynamic and initial safety analysis of (−)-epicatechin in healthy volunteers-Reference-Cited by-同舟云学术

Pharmacokinetic, partial pharmacodynamic and initial safety analysis of (−)-epicatechin in healthy volunteers

Published:2015 Issue:3 Volume:6 Page:824-833
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Barnett Christopher F.¹²³,Moreno-Ulloa Aldo¹⁴⁵³⁶,Shiva Sruti⁷⁸³,Ramirez-Sanchez Israel¹⁴⁵³⁶,Taub Pam R.¹⁴⁵³,Su Yongxuan¹⁹⁴³,Ceballos Guillermo⁶¹⁰¹¹¹²,Dugar Sundeep¹³¹⁴³,Schreiner George¹³¹⁴³,Villarreal Francisco¹⁴⁵³

Affiliation:

1. University of California

2. San Francisco

3. USA

4. San Diego

5. School of Medicine

6. Escuela Superior de Medicina del Instituto Politécnico Nacional

7. Department of Pharmacology & Chemical Biology and Vascular Medicine Institute

8. University of Pittsburgh

9. Chemistry and Biochemistry

10. Seccion de Posgrado

11. Mexico City

12. Mexico

13. Cardero Therapeutics

14. Inc.

Abstract

(−)-Epicatechin ((−)-EPI), a naturally occurring flavanol, has emerged as a likely candidate for cocoa-based product reported reductions in cardiometabolic risk.

Funder

National Institutes of Health

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

Link

http://pubs.rsc.org/en/content/articlepdf/2015/FO/C4FO00596A

Reference25 articles.

1. Cocoa and Chocolate in Human Health and Disease

2. Chocolate consumption and cardiometabolic disorders: systematic review and meta-analysis

3. Effects of chocolate, cocoa, and flavan-3-ols on cardiovascular health: a systematic review and meta-analysis of randomized trials