Platelet-derived nanovesicles for hemostasis without release of pro-inflammatory cytokines-Reference-Cited by-同舟云学术

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Platelet-derived nanovesicles for hemostasis without release of pro-inflammatory cytokines

Published:2019 Issue:3 Volume:7 Page:856-859
ISSN:2047-4830
Container-title:Biomaterials Science
language:en
Short-container-title:Biomater. Sci.

Author:

Jung Heesun¹²³⁴,Kang Yoon Young¹²³⁴,Mok Hyejung¹²³⁴^ORCID

Affiliation:

1. Department of Bioscience and Biotechnology

2. Konkuk University

3. Gwangjin-gu

4. Republic of Korea

Abstract

In this study, natural platelet-derived nanovesicles with a vacant core were prepared by hypotonic sonication. The nanovesicles efficiently formed platelet-like aggregates without a notable release of pro-inflammatory cytokines. These natural and biocompatible platelet-derived nanovesicles have great potential as biomaterials for inflammation-free injectable hemostasis.

Funder

Ministry of Education, Science and Technology

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

Link

http://pubs.rsc.org/en/content/articlepdf/2019/BM/C8BM01480A

Reference29 articles.

1. Approaches to synthetic platelet analogs

2. In vitro and in vivo hemostatic capabilities of a functionally integrated platelet-mimetic liposomal nanoconstruct

3. The antithrombotic effect of aprotinin: actions mediated via the protease-activated receptor 1

4. The growing complexity of platelet aggregation

5. Arterial thrombosis—insidious, unpredictable and deadly

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