Changes in the cardiac metabolome caused by perhexiline treatment in a mouse model of hypertrophic cardiomyopathy-Reference-Cited by-同舟云学术

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Changes in the cardiac metabolome caused by perhexiline treatment in a mouse model of hypertrophic cardiomyopathy

Published:2015 Issue:2 Volume:11 Page:564-573
ISSN:1742-206X
Container-title:Molecular BioSystems
language:en
Short-container-title:Mol. BioSyst.

Author:

Gehmlich Katja¹²³⁴⁵,Dodd Michael S.⁶⁷⁸³⁴,William Allwood J.⁹¹⁰¹¹⁵,Kelly Matthew¹²³⁴⁵,Bellahcene Mohamed¹²³⁴⁵,Lad Heena V.¹²³⁴⁵,Stockenhuber Alexander¹²³⁴⁵,Hooper Charlotte¹²³⁴⁵,Ashrafian Houman¹²³⁴⁵,Redwood Charles S.¹²³⁴⁵,Carrier Lucie¹²¹³¹⁴¹⁵¹⁶,Dunn Warwick B.⁹¹⁰¹¹⁵

Affiliation:

1. Division of Cardiovascular Medicine

2. Radcliffe Department of Medicine

3. University of Oxford

4. Oxford

5. UK

6. Cardiac Metabolism Research Group

7. Department of Physiology

8. Anatomy & Genetics

9. School of Biosciences

10. University of Birmingham

11. Birmingham

12. Department of Experimental Pharmacology and Toxicology

13. Cardiovascular Research Centre

14. University Medical Center

15. Hamburg-Eppendorf

16. Hamburg

Abstract

Perhexiline induces a distinct metabolic phenotype change in a mouse model of hypertrophic cardiomyopathy as defined by a metabolomics approach.

Funder

British Heart Foundation

European Commission

Publisher

Royal Society of Chemistry (RSC)

Subject

Molecular Biology,Biotechnology

Link

http://pubs.rsc.org/en/content/articlepdf/2015/MB/C4MB00594E

Reference36 articles.

1. Hypertrophic Cardiomyopathy

2. Hypertrophic cardiomyopathy

3. Inherited Cardiomyopathies

4. Hypertrophic Cardiomyopathy

5. Commentary and Re-Appraisal: Surgical Septal Myectomy Vs. Alcohol Ablation: After a Decade of Controversy and Mismatch Between Clinical Practice and Guidelines

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