Beneficial effects of Dendrobium officinale on metabolic hypertensive rats by triggering the enteric-origin SCFA-GPCR43/41 pathway-Reference-Cited by-同舟云学术

Beneficial effects of Dendrobium officinale on metabolic hypertensive rats by triggering the enteric-origin SCFA-GPCR43/41 pathway

Published:2021 Issue:12 Volume:12 Page:5524-5538
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Li Bo¹²³⁴⁵,He Xinglishang¹²³,Jin Hai-Ying⁶⁷³,Wang Hui-Ying¹²³^ORCID,Zhou Fu-Chen¹²³,Zhang Ning-Yu¹²³,Jie Dong-Ying¹²³,Li Lin-Zi¹²³,Su Jie⁸²³^ORCID,Zheng Xiang¹²³,Luo Rong¹²³,Lv Gui-Yuan⁸²³,Jiang Ning-Hua⁹¹⁰³,Yu Qiao-Xian⁶⁷³,Chen Su-Hong¹²³⁴⁵

Affiliation:

1. Zhejiang University of Technology

2. Hangzhou

3. PR China

4. Zhejiang Synergetic Traditional Chinese Medicine Research and Development Co., Ltd

5. Deqing

6. Zhejiang Senyu Co., Ltd

7. Yiwu

8. Zhejiang Chinese Medical University

9. The second affiliated hospital of Jia xing university

10. Jiaxing, 314001

Abstract

DOFP enhances the production of SCFAs and absorption from the intestines and then activates the SCFA-GPCR43/41 pathway, resulting in improvements in vascular endothelial function and reduction in blood pressure of the ACHSFD-induced MH rats.

Funder

National Natural Science Foundation of China

National Key Research and Development Program of China

Natural Science Foundation of Zhejiang Province

Zhejiang Provincial Ten Thousand Plan for Young Top Talents

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

Link

http://pubs.rsc.org/en/content/articlepdf/2021/FO/D0FO02890H

Reference48 articles.