Non-natural amino acid peptide microarrays to discover Ebola virus glycoprotein ligands

Author:

Rabinowitz Joshua A.1234ORCID,Lainson John C.1234ORCID,Johnston Stephen Albert1234,Diehnelt Chris W.1234ORCID

Affiliation:

1. Biodesign Institute Center for Innovations in Medicine

2. Arizona State University

3. Tempe

4. USA

Abstract

We demonstrate a platform to screen a virus pseudotyped with Ebola virus glycoprotein (GP) against a library of peptides that contain non-natural amino acids to develop GP affinity ligands.

Funder

Defense Advanced Research Projects Agency

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

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