Highly efficient regio and diastereoselective synthesis of functionalized bis-spirooxindoles and their antibacterial properties
Author:
Affiliation:
1. Inorganic and Physical Chemistry Division
2. CSIR-Indian Institute of Chemical Technology
3. Hyderabad 500007
4. India
5. Bio Engineering and Environmental Centre
6. Laboratory of X-ray Crystallography
7. Hyderabad-500007
Abstract
A simple, efficient, regioselective and diastereoselective method has been developed for the synthesis of spirooxindole-pyrrolidines using 0.5 mol% of ceric ammonium nitrate in aqueous medium.
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemical Engineering,General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2016/RA/C6RA00613B
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4. Combinatorial Synthesis of Functionalized Spirooxindole-Pyrrolidine/Pyrrolizidine/Pyrrolothiazole Derivatives via Three-Component 1,3-Dipolar Cycloaddition Reactions
5. Discovery of Antimycobacterial Spiro-piperidin-4-ones: An Atom Economic, Stereoselective Synthesis, and Biological Intervention
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