A versatile access to vicinal diamine motifs by highly anti-selective asymmetric vinylogous Mannich reactions: an efficient total synthesis of (+)-absouline-Reference-Cited by-同舟云学术

A versatile access to vicinal diamine motifs by highly anti-selective asymmetric vinylogous Mannich reactions: an efficient total synthesis of (+)-absouline

Published:2016 Issue:6 Volume:3 Page:683-692
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Ye Jian-Liang¹²³⁴⁵,Chen Hang¹²³⁴⁵,Zhang Yu-Feng¹²³⁴⁵,Huang Pei-Qiang¹²³⁴⁵

Affiliation:

1. Department of Chemistry and Fujian Provincial Key Laboratory of Chemical Biology

2. iChEM (Collaborative Innovation Center of Chemistry for Energy Materials)

3. College of Chemistry and Chemical Engineering

4. Xiamen University

5. Xiamen

Abstract

An anti-stereoselective vinylogous Mannich reaction between 2-TBSO-pyrrole and N-tert-butanesulfinyl imines and its application to the efficient synthesis of (+)-absouline were reported.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/QO/C6QO00022C

Reference62 articles.

1. The Chemistry of Vicinal Diamines

2. Catalytic Enantioselective Aza‐Henry Reactions

3. Update 1 of: α,β-Diamino Acids: Biological Significance and Synthetic Approaches

4. Methods for direct alkene diamination, new & old

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