Bio-catalytic synthesis of unnatural nucleosides possessing a large functional group such as a fluorescent molecule by purine nucleoside phosphorylase
Author:
Affiliation:
1. Department of Chemistry
2. Shibaura Institute of Technology
3. Saitama
4. Japan
Abstract
Unnatural nucleosides are attracting interest as potential diagnostic tools, medicines, and functional molecules.
Funder
JSPS
Publisher
Royal Society of Chemistry (RSC)
Subject
Catalysis
Link
http://pubs.rsc.org/en/content/articlepdf/2019/CY/C9CY01063G
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2. C. Simons , Nucleoside Mimetics , Gordon & Breach Science , 2001 , ch. 1, pp. 23–27
3. Nucleotide- and nucleoside-converting ectoenzymes: Important modulators of purinergic signalling cascade
4. Trans-N-Deoxyribosylase: Purification by Affinity Chromatography and Characterization
5. The stereoselective enzymatic synthesis of 9-β-d-2′-deoxyribofuranosyl 1-deazapurine
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