Coordinating activation strategy enables 1,2-alkylamidation of alkynes-Reference-Cited by-同舟云学术

Coordinating activation strategy enables 1,2-alkylamidation of alkynes

Published:2023 Issue:41 Volume:14 Page:11466-11473
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Ren Jing¹,Xu Junhua¹,Kong Xiangxiang¹,Li Jinlong¹,Li Kaizhi¹^ORCID

Affiliation:

1. Biopharmaceutical Research Institute, West China Hospital of Sichuan University, 37 Guoxue Alley, Chengdu, 610041, P. R. China

Abstract

The radical 1,2-difunctional alkylamidation of alkynes has been developed with the help of a bidentate coordinating group for the synthesis of β-alkylated enamides.

Funder

Science and Technology Department of Sichuan Province

National Natural Science Foundation of China

West China Hospital, Sichuan University

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/SC/D3SC03786J

Reference91 articles.

1. Lobatamide C: Total Synthesis, Stereochemical Assignment, Preparation of Simplified Analogues, and V-ATPase Inhibition Studies

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3. Isolation and First Total Synthesis of PM050489 and PM060184, Two New Marine Anticancer Compounds

4. Cu-mediated enamide formation in the total synthesis of complex peptide natural products

5. Enamides and Enecarbamates as Nucleophiles in Stereoselective C–C and C–N Bond-Forming Reactions

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