Total Synthesis of TMC-95A and -B via a New Reaction Leading to Z-Enamides. Some Preliminary Findings as to SAR-Reference-Cited by-同舟云学术

Total Synthesis of TMC-95A and -B via a New Reaction Leading to Z-Enamides. Some Preliminary Findings as to SAR

Published:2004-04-27 Issue:20 Volume:126 Page:6347-6355
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Lin Songnian¹,Yang Zhi-Qiang¹,Kwok Benjamin H. B.¹,Koldobskiy Michael¹,Crews Craig M.¹,Danishefsky Samuel J.¹

Affiliation:

1. Contribution from the Laboratory for Bioorganic Chemistry, Sloan Kettering Institute for Cancer Research, 1275 York Avenue, New York, New York 10021, Department of Chemistry, Columbia University, Havemayer Hall, 3000 Broadway, New York, New York 10027, and Department of Molecular, Cellular and Developmental Biology, Pharmacology, and Chemistry, Yale University, 219 Prospect Street, New Haven, Connecticut 06520-8103

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Link

https://pubs.acs.org/doi/pdf/10.1021/ja049821k

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1. Lactacystin and clasto-Lactacystin β-Lactone Modify Multiple Proteasome β-Subunits and Inhibit Intracellular Protein Degradation and Major Histocompatibility Complex Class I Antigen Presentation

2. STRUCTURE AND FUNCTIONS OF THE 20S AND 26S PROTEASOMES

3. The ubiquitin-proteasome pathway: on protein death and cell life

4. The ubiquitin-proteasome pathway and proteasome inhibitors

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