Monitoring cytosolic and ER Zn2+ in stimulated breast cancer cells using genetically encoded FRET sensors-Reference-Cited by-同舟云学术

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Monitoring cytosolic and ER Zn2+ in stimulated breast cancer cells using genetically encoded FRET sensors

Published:2016 Issue:2 Volume:8 Page:211-217
ISSN:1756-5901
Container-title:Metallomics
language:en
Short-container-title:Metallomics

Author:

Hessels Anne M.¹²³⁴,Taylor Kathryn M.⁵⁶⁷⁸,Merkx Maarten¹²³⁴

Affiliation:

1. Laboratory of Chemical Biology and Institute of Complex Molecular Systems (ICMS)

2. Department of Biomedical Engineering

3. Eindhoven University of Technology

4. Eindhoven, The Netherlands

5. Breast Cancer Molecular Pharmacology Group

6. School of Pharmacy and Pharmaceutical Sciences

7. Cardiff University

8. Cardiff, UK

Abstract

Unexpectedly, monitoring cytosolic and ER Zn²⁺ using FRET sensor proteins does not support EGF–ionomycin-triggered Zn²⁺ waves in breast cancer cells.

Funder

European Research Council

Nederlandse Organisatie voor Wetenschappelijk Onderzoek

Publisher

Oxford University Press (OUP)

Subject

Metals and Alloys,Biochemistry,Biomaterials,Biophysics,Chemistry (miscellaneous)

Link

http://pubs.rsc.org/en/content/articlepdf/2016/MT/C5MT00257E

Reference26 articles.

1. Zinc coordination, function, and structure of zinc enzymes and other proteins

2. Zinc is a novel intracellular second messenger

3. Zinc transporter LIVI controls epithelial-mesenchymal transition in zebrafish gastrula organizer

4. Zinc transporters and cancer: a potential role for ZIP7 as a hub for tyrosine kinase activation

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