Dimeric naphthylisoquinoline alkaloids: polyketide-derived axially chiral bioactive quateraryls

Author:

Lombe Blaise Kimbadi12345ORCID,Feineis Doris1234,Bringmann Gerhard1234ORCID

Affiliation:

1. Institute of Organic Chemistry

2. University of Würzburg

3. D-97074 Würzburg

4. Germany

5. Faculté des Sciences

Abstract

This is the first review on dimeric naphthylisoquinolines, a group of structurally intriguing, biosynthetically unique, and pharmacologically promising alkaloids.

Funder

Deutscher Akademischer Austauschdienst

Deutsche Forschungsgemeinschaft

Else Kröner-Fresenius-Stiftung

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Reference171 articles.

1. G. Bringmann and F.Pokorny , in The Alkaloids: Chemistry and Pharmacology , ed. G. A. Cordell , Academic Press Inc. , New York , 1995 , vol. 46 , pp. 127–271

2. G. Bringmann , C.Günther , M.Ochse , O.Schupp and S.Tasler , in Progress in the Chemistry of Organic Natural Products , ed. W. Herz , H. Falk , G. W. Kirby and R. E. Moore , Springer Vienna , Vienna , 2001 , pp. 1–249

3. Naphthylisoquinoline alkaloids potential drug leads

4. Ancistrocladine, a new type of isoquinoline alkaloid from Ancistrocladus heyneanus

5. Ancistrocladinium A and B, the First N,C-Coupled Naphthyldihydroisoquinoline Alkaloids, from a Congolese Ancistrocladus Species

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