Leveraging cascade alkynyl Prins cyclization towards the stereoselective synthesis of spiro-furan quinazolinone scaffolds-Reference-Cited by-同舟云学术

Leveraging cascade alkynyl Prins cyclization towards the stereoselective synthesis of spiro-furan quinazolinone scaffolds

Published:2023 Issue:96 Volume:59 Page:14301-14304
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Biswas Subhamoy¹^ORCID,Shit Sudip¹^ORCID,Behera Bipin Kumar¹^ORCID,Sahu Archana Kumari¹^ORCID,Saikia Anil K.¹^ORCID

Affiliation:

1. Department of Chemistry, Indian Institute of Technology Guwahati, Guwahati-781039, Assam, India

Abstract

Highly functionalized spiro-furan quinazolinone scaffolds employing cascade alkynyl Prins cyclization reaction with an exocyclic double bond in excellent yields and exclusive selectivity are revealed.

Funder

Science and Engineering Research Board

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2023/CC/D3CC04464E

Reference49 articles.

1. Synthetic Routes to Approved Drugs Containing a Spirocycle

2. Spirocyclic Scaffolds in Medicinal Chemistry

3. Spirocyclic Motifs in Natural Products

4. The use of spirocyclic scaffolds in drug discovery

5. New development in the enantioselective synthesis of spiro compounds

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