Chemistry and biology of microsomal prostaglandin E2 synthase-1 (mPGES-1) inhibitors as novel anti-inflammatory agents: recent developments and current status-Reference-Cited by-同舟云学术

Chemistry and biology of microsomal prostaglandin E2 synthase-1 (mPGES-1) inhibitors as novel anti-inflammatory agents: recent developments and current status

Published:2016 Issue:34 Volume:6 Page:28343-28369
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Khurana Puneet¹²³⁴,Jachak Sanjay M.¹²³⁴

Affiliation:

1. Department of Natural Products

2. National Institute of Pharmaceutical Education and Research (NIPER)

3. Mohali-160062

4. India

Abstract

Prostaglandin (PG) E₂, a key mediator of inflammatory pain and fever, is biosynthesized from PGH₂ by mPGES-1.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/RA/C5RA25186A

Reference124 articles.

1. G. Majno and I.Joris, Cells, tissues, and disease: principles of general pathology, Oxford University Press, New York, 2nd edn, 2004, pp. 307–370

2. Recent developments in anti-inflammatory natural products

3. The eicosanoids and their biochemical mechanisms of action

4. Prostaglandins in Health and Disease: An Overview

5. Prostaglandin E2 synthesis and secretion: The role of PGE2 synthases

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