4-Hydrazinoquinazoline acting as a reactive matrix for the rapid and sensitive analysis of neutral and sialylated glycans using MALDI MS-Reference-Cited by-同舟云学术

4-Hydrazinoquinazoline acting as a reactive matrix for the rapid and sensitive analysis of neutral and sialylated glycans using MALDI MS

Published:2021 Issue:22 Volume:146 Page:6840-6845
ISSN:0003-2654
Container-title:The Analyst
language:en
Short-container-title:Analyst

Author:

Ling Ling¹^ORCID,Yu Shaoning¹,Ding Chuanfan¹

Affiliation:

1. Key Laboratory of Advanced Mass Spectrometry and Molecular Analysis of Zhejiang Province, Institute of Mass Spectrometry, School of Material Science and Chemical Engineering, Ningbo University, Ningbo 315211, China

Abstract

A reactive MALDI matrix 4-hydrazinoquinazoline was used for the enhanced detection of both neutral and sialylated glycans via the dried-droplet method.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrochemistry,Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/AN/D1AN01452H

Reference32 articles.

1. Global view of human protein glycosylation pathways and functions

2. Emerging Principles for the Therapeutic Exploitation of Glycosylation

3. Glycosylation in cancer: mechanisms and clinical implications