Affiliation:
1. Oxford Glycobiology Institute, Department of Biochemistry, University of Oxford, South Parks Road, Oxford OX1 3QU, UK.
Abstract
Understanding Glycosylation
Glycosylation—the covalent addition of carbohydrates to proteins—is central to many biological processes. Recent advances in understanding the roles of glycans—for example, in protein folding and immune regulation—have revealed that glycans are also involved in many disease conditions, from cancer to microbial infection.
Dalziel
et al.
(p.
10.1126/science.1235681
) review the current knowledge of glycans in pathogen invasion, cancer, autoimmunity, and congenital diseases.
Publisher
American Association for the Advancement of Science (AAAS)
Cited by
381 articles.
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