Metal-free oxidative acylation/cyclization of N-methacryloyl-2-phenylbenzoimidazole with aryl aldehydes: an easy access to benzimidazo[2,1-a]isoquinolin-6(5H)-ones-Reference-Cited by-同舟云学术

Metal-free oxidative acylation/cyclization of N-methacryloyl-2-phenylbenzoimidazole with aryl aldehydes: an easy access to benzimidazo[2,1-a]isoquinolin-6(5H)-ones

Published:2019 Issue:44 Volume:17 Page:9627-9630
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Boora Ramesh¹²³⁴,kumar G. Ravi¹²³⁴,Subba Reddy B. V.¹²³⁴^ORCID

Affiliation:

1. Centre for Semiochemicals

2. CSIR-Indian Institute of Chemical Technology

3. Hyderabad–500 007

4. India

Abstract

A metal-free radical cyclization strategy has been developed for the synthesis of fused benzimidazo[2,1-a]isoquinolin-6(5H)-one derivatives using 70% tert-butylhydroperoxide in water (TBHP).

Funder

University Grants Commission

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/OB/C9OB01979K

Reference38 articles.

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2. Biologically active isoquinoline alkaloids with drug-like properties from the genus Corydalis

3. A domino green method for the rapid synthesis of novel fused isoquinoline derivatives via Knoevenagel/Michael/cyclization reactions on aqueous media and their photophysical properties