Synthesis and antiviral activity of camphor-based 1,3-thiazolidin-4-one and thiazole derivatives as Orthopoxvirus-reproduction inhibitors
Author:
Affiliation:
1. Novosibirsk Institute of Organic Chemistry
2. Siberian Branch of the Russian Academy of Sciences
3. 630090 Novosibirsk
4. Russia
5. Novosibirsk State University
6. State Research Center of Virology and Biotechnology VECTOR
7. Koltsovo
Abstract
Camphor based heterocyclic systems containing 1,3-thiazolidin-4-one and thiazole rings showed promising antiviral activity towards Orthopoxviruses.
Funder
Russian Science Foundation
Publisher
Royal Society of Chemistry (RSC)
Subject
Pharmaceutical Science,Biochemistry,Drug Discovery,Molecular Medicine,Pharmacology,Organic Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2018/MD/C8MD00347E
Reference18 articles.
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4. Efficacy of Tecovirimat (ST-246) in Nonhuman Primates Infected with Variola Virus (Smallpox)
5. Chemistry and heterocyclization of thiosemicarbazones
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