A highly effective method for the environmentally friendly production of novel chromene derivatives using electron deficient compounds

Author:

Shafaei Faezeh1,Hargalani Fariba Zamani2,Ghazvini Maryam3ORCID

Affiliation:

1. Department of Chemistry, East Tehran Branch Islamic Azad University Tehran Iran

2. Department of Natural Resources and Environment, Science and Research Branch Islamic Azad University Tehran Iran

3. Department of Chemistry Payame Noor University Tehran Iran

Abstract

AbstractNew, high‐yield derivatives of oxepino[3,2‐c]chromene were synthesized through a multicomponent reaction. This reaction involved 2‐hydroxyacetophenone, dimethyl carbonate, activated acetylenic compounds, and alkyl bromide. The reaction took place at room temperature in an aqueous environment, resulting in the formation of these innovative compounds. Oxathiepines were synthesized using multicomponent reactions of 2‐hydroxyacetophenone, dimethyl carbonate, isothiocyanate, and alkyl bromide in water at room temperature. This technology offers several benefits, including quick response times, high product yields, and easy product separation using straightforward techniques.

Publisher

Wiley

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