Synthesis and serum protein binding of novel ring-substituted harmine derivatives
Author:
Affiliation:
1. Research Group of Chemical Biology
2. Institute of Organic Chemistry
3. Research Centre for Natural Sciences
4. Hungarian Academy of Sciences
5. Budapest
6. Servier Research Institute of Medicinal Chemistry
7. Hungary
Abstract
Potential anticancer derivatives of the β-carboline alkaloid harmine exhibit substituent dependent serum protein binding.
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemical Engineering,General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2015/RA/C5RA06426K
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5. β-Carboline Compounds, Including Harmine, Inhibit DYRK1A and Tau Phosphorylation at Multiple Alzheimer's Disease-Related Sites
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