Facile fabrication of reduction-responsive nanocarriers for controlled drug release

Author:

Sun Rui1234,Luo Qiaojie56738,Gao Chen1234,Wang Ying1234,Gao Lilong1234,Du Hong1234,Huang Ying56738,Li Xiaodong56738,Shen Zhiquan1234,Zhu Weipu1234

Affiliation:

1. MOE Key Laboratory of Macromolecular Synthesis and Functionalization

2. Department of Polymer Science and Engineering

3. Zhejiang University

4. Hangzhou 310027, People's Republic of China

5. Department of Oral and Maxillofacial Surgery

6. Affiliated Stomatology Hospital

7. College of Medicine

8. Hangzhou 310006, P. R. China

Abstract

An amphiphilic multiblock poly(ether–ester) containing multiple thiols was facilely synthesized by “one-pot” polycondensation, and was used to prepare reduction-responsive core-crosslinked micelles for controlled drug release.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Polymers and Plastics,Biochemistry,Bioengineering

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