Towards a sustainable generation of pseudopterosin-type bioactives

Author:

Ringel Marion12345ORCID,Reinbold Markus12345,Hirte Max12345,Haack Martina12345,Huber Claudia62375,Eisenreich Wolfgang62375,Masri Mahmoud A.12345ORCID,Schenk Gerhard891011ORCID,Guddat Luke W.891011,Loll Bernhard121314155ORCID,Kerr Russell1617181920,Garbe Daniel12345ORCID,Brück Thomas12345ORCID

Affiliation:

1. Werner Siemens Chair of Synthetic Biotechnology

2. Dept. of Chemistry

3. Technical University of Munich (TUM)

4. 85748 Garching

5. Germany

6. Chair of Biochemistry

7. 85478 Garching

8. School of Chemistry and Molecular Biosciences

9. The University of Queensland

10. 4702 Brisbane

11. Australia

12. Institute for Chemistry and Biochemistry

13. Laboratory of Structural Biochemistry

14. Freie Universität Berlin

15. 14195 Berlin

16. Department of Chemistry

17. and Department of Biomedical Sciences

18. Atlantic Veterinary College

19. University of Prince Edward Island

20. Charlottetown

Abstract

Pseudopterosins (Ps), marine diterpene glycosides derived from the marine octocoral Antillogorgia elisabethae, have potent anti-inflammatory activity demonstrated in phase II clinical trials.

Funder

Bundesministerium für Bildung und Forschung

Publisher

Royal Society of Chemistry (RSC)

Subject

Pollution,Environmental Chemistry

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