Synthesis and immunopharmacological evaluation of novel TLR7 agonistic triazole tethered imidazoquinolines-Reference-Cited by-同舟云学术

Synthesis and immunopharmacological evaluation of novel TLR7 agonistic triazole tethered imidazoquinolines

Published:2023 Issue:2 Volume:13 Page:1066-1077
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Avoni Ayyappa¹²,Vemireddy Sravanthi¹,Sambyal Shainy¹,Shafi Syed³,Khan Imran³,Khan Aarif³,Sampath Kumar Halmuthur M.¹²^ORCID

Affiliation:

1. Vaccine Immunology Laboratory, OSPC Division, CSIR-Indian Institute of Chemical Technology, Hyderabad 500007, India

2. Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, Uttar Pradesh 201 002, India

3. Department of Chemistry, Hamdard University, Hamdard Nagar, New Delhi, Delhi 110062, India

Abstract

Toll-like receptors-7 and -8 are expressed abundantly on antigen-presenting cells, and their agonists make potential adjuvant candidates for the development of new efficacious vaccines.

Funder

Department of Biotechnology, Ministry of Science and Technology, India

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/RA/D2RA06395F

Reference26 articles.

1. The use of Toll-like receptor 7/8 agonists as vaccine adjuvants

2. Toll-like receptors: the swiss army knife of immunity and vaccine development

3. TLR Agonists as Vaccine Adjuvants Targeting Cancer and Infectious Diseases

4. Structure–Activity Relationships in Human Toll-like Receptor 8-Active 2,3-Diamino-furo[2,3-c]pyridines

5. Structural evolution of toll-like receptor 7/8 agonists from imidazoquinolines to imidazoles

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