High-throughput production of two disulphide-bridge toxins-Reference-Cited by-同舟云学术

High-throughput production of two disulphide-bridge toxins

Published:2014 Issue:61 Volume:50 Page:8408-8411
ISSN:1359-7345
Container-title:Chem. Commun.
language:en
Short-container-title:Chem. Commun.

Author:

Upert Grégory¹²,Mourier Gilles¹²,Pastor Alexandra¹²,Verdenaud Marion³²,Alili Doria¹²,Servent Denis¹²,Gilles Nicolas¹²

Affiliation:

1. CEA, DSV, iBiTec-S, Service d'Ingénierie Moléculaire des Protéines (SIMOPRO)

2. Gif sur Yvette F-91191, France

3. CEA, DSV, iBiTec-S, Service de Pharmacologie et d'Immunoanalyse

Abstract

A quick and efficient production method compatible with high-throughput screening was developed using 36 toxins belonging to four different families of two disulphide-bridge toxins. Final toxins were characterized using HPLC co-elution, CD and pharmacology studies.

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2014/CC/C4CC02679A

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