From a Cone Snail Toxin to a Competitive MC4R Antagonist-Reference-Cited by-同舟云学术

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From a Cone Snail Toxin to a Competitive MC4R Antagonist

Published:2022-09-05 Issue:18 Volume:65 Page:12084-12094
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Reynaud Steve¹^ORCID,Laurin Suli-Anne²^ORCID,Ciolek Justyna¹,Barbe Peggy¹,Van Baelen Anne-Cécile¹,Susset Michaël¹,Blondel Florian¹,Ghazarian Marine¹,Boeri Julia¹,Vanden Driessche Margot¹,Upert Grégory¹,Mourier Gilles¹,Kessler Pascal¹,Konnert Laure³,Beroud Rémy³,Keck Mathilde¹^ORCID,Servent Denis¹,Bouvier Michel²^ORCID,Gilles Nicolas¹^ORCID

Affiliation:

1. Health and Life Sciences Department, Université Paris Saclay, French Alternative Energies and Atomic Energy Commission (CEA), CEA Saclay, Bat 152, 91191 Gif sur Yvette, France

2. Institute for Research in Immunology and Cancer, Department of Biochemistry and Molecular Medicine, Université de Montréal, Montréal, Québec H3T 1J4, Canada

3. Smartox Biotechnology, 6 Rue des Platanes, 38120 Saint-Egrève, France

Funder

Canadian Institutes of Health Research

Fonds de Recherche du Qu?bec - Sant?

FP7 Health

Universit? de Paris

Canada Research Chairs

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.2c00786

Reference49 articles.

1. A neural basis for melanocortin-4 receptor–regulated appetite

2. The Role of the Melanocortin System in Metabolic Disease: New Developments and Advances

3. Melanocortin Receptor 4 Signaling Regulates Vertebrate Limb Regeneration

4. RM-493, a Melanocortin-4 Receptor (MC4R) Agonist, Increases Resting Energy Expenditure in Obese Individuals

5. Clinical Spectrum of Obesity and Mutations in the Melanocortin 4 Receptor Gene

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1. Natural Peptide Toxins as an Option for Renewed Treatment of Type 2 Vasopressin Receptor-Related Diseases;Biology;2023-04-03

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