A multicomponent macrocyclization strategy to natural product-like cyclic lipopeptides: synthesis and anticancer evaluation of surfactin and mycosubtilin analogues
Author:
Affiliation:
1. Department of Bioorganic Chemistry
2. Leibniz Institute of Plant Biochemistry
3. Halle/Saale
4. Germany
5. Center for Natural Products Research
6. Center for Protein Studies
7. Faculty of Biology
8. University of Havana
9. Havana
10. Cuba
Abstract
Two birds in one shot: oligopeptides can be cyclized and lipidated in one step with multicomponent reactions.
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2017/OB/C7OB00459A
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5. What can a chemist learn from nature?s macrocycles? ? A brief, conceptual view
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