The evolution of fibrin-specific targeting strategies
Author:
Affiliation:
1. The Wallace H. Coulter Department of Biomedical Engineering
2. Georgia Institute of Technology and Emory University
3. Atlanta
4. USA
5. The Parker H. Petit Institute for Bioengineering and biosciences
Abstract
A variety of antibodies, antibody fragments, and small peptides have been engineered to specifically target fibrin over its precursor fibrinogen.
Funder
National Institutes of Health
Publisher
Royal Society of Chemistry (RSC)
Subject
General Materials Science,Biomedical Engineering,General Chemistry,General Medicine
Link
http://pubs.rsc.org/en/content/articlepdf/2015/TB/C4TB01769B
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1. Fibrinogen is an important determinant of the metastatic potential of circulating tumor cells
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4. Roles of fibrin deposition and protease activated receptor-1 in renal cytokine/chemokine production and inflammatory cell infiltration in rats of different ages
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