Multivalent aptamer-modified tetrahedral DNA nanocage demonstrates high selectivity and safety for anti-tumor therapy
Author:
Affiliation:
1. Key Laboratory of Modern Chinese Medicines
2. China Pharmaceutical University
3. Nanjing 210009
4. PR China
5. Cellular and Molecular Biology Center
6. Jiangning Campus
7. High School Affiliated to Nanjing Normal University
8. Nanjing 211102
Abstract
Multivalent aptamer-modified tetrahedral DNA nanocage demonstrates high selectivity and safety for anti-tumor therapyin vivo.
Funder
National Natural Science Foundation of China
Publisher
Royal Society of Chemistry (RSC)
Subject
General Materials Science
Link
http://pubs.rsc.org/en/content/articlepdf/2019/NR/C8NR05546G
Reference32 articles.
1. DNA Origami as a Carrier for Circumvention of Drug Resistance
2. A dual-targeting DNA tetrahedron nanocarrier for breast cancer cell imaging and drug delivery
3. DNA Origami as an In Vivo Drug Delivery Vehicle for Cancer Therapy
4. Daunorubicin-Loaded DNA Origami Nanostructures Circumvent Drug-Resistance Mechanisms in a Leukemia Model
5. Growth and Origami Folding of DNA on Nanoparticles for High-Efficiency Molecular Transport in Cellular Imaging and Drug Delivery
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