Synthesis and antiproliferative evaluation of novel tetrahydrobenzo[4′,5′]thieno[3′,2′:5,6]pyrido[4,3-d]pyrimidine derivatives-Reference-Cited by-同舟云学术

Synthesis and antiproliferative evaluation of novel tetrahydrobenzo[4′,5′]thieno[3′,2′:5,6]pyrido[4,3-d]pyrimidine derivatives

Published:2014 Issue:55 Volume:4 Page:29187-29192
ISSN:2046-2069
Container-title:RSC Adv.
language:en
Short-container-title:RSC Adv.

Author:

Tang Chu¹²³⁴,Liang Yongju⁵⁶⁷,Bai Shun⁸³⁴,He Hongwu⁹¹⁰¹¹,Chen Yu⁸³⁴,Yang Guangzhong¹²³⁴,Fu Liwu⁵⁶⁷

Affiliation:

1. Laboratory for Natural Product Chemistry

2. College of Pharmacy

3. South Central University for Nationalities

4. Wuhan 430074, P. R. China

5. State Key Laboratory of Oncology in South China

6. Cancer Center, Sun Yat-sen University

7. Guangzhou 510060, P. R. China

8. College of Chemistry and Material Sciences

9. College of Chemistry

10. Central China Normal University

11. Wuhan 430079, P. R. China

Abstract

A series of tetrahydrobenzo[4′,5′]thienophene[3′,2′:5,6]pyrido[4,3-d]pyrimidine-4-(3H)-one derivatives were synthesized and evaluated for their antiproliferative activities.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2014/RA/C4RA03535F

Reference21 articles.

1. American Cancer Society, Atlanta, Cancer Facts & Figures, 2012, http://www.cancer.org/acs/groups/content/@epidemiologysurveilance/documents/document/acspc-031941.pdf

2. Phase 1 clinical results with tandutinib (MLN518), a novel FLT3 antagonist, in patients with acute myelogenous leukemia or high-risk myelodysplastic syndrome: safety, pharmacokinetics, and pharmacodynamics

3. Discovery of Pteridin-7(8H)-one-Based Irreversible Inhibitors Targeting the Epidermal Growth Factor Receptor (EGFR) Kinase T790M/L858R Mutant

4. Design and Synthesis of Tetrahydropyridothieno[2,3-d]pyrimidine Scaffold Based Epidermal Growth Factor Receptor (EGFR) Kinase Inhibitors: The Role of Side Chain Chirality and Michael Acceptor Group for Maximal Potency

Cited by 5 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Three Heterocyclic Rings Fused (5-6-6);Comprehensive Heterocyclic Chemistry IV;2022

2. Synthesis, photophysical, solvatochromic and DFT studies of (Z)-2-(2-Phenyl-4H-benzo[4,5]thiazolo[3,2-a]pyrimidin-4-ylidene)acetonitrile derivatives;Journal of Luminescence;2019-06

3. Facile Microwave-Assisted Synthesis of 6, 7-Dihydro-5H-cyclopenta [4, 5]thieno [2, 3-d]pyrimidin-4-amine;Chinese Journal of Organic Chemistry;2018

4. Synthesis, molecular structure and spectroscopic characterization of (E)-1-((2-hydroxynaphthalen-1-yl) methyleneamino)-5-(4-methoxybenzoyl)-4-(4-methoxyphenyl) pyrimidine-2(1H)-one with experimental techniques and theoretical calculations;Journal of Molecular Structure;2016-04

5. ChemInform Abstract: Synthesis and Antiproliferative Evaluation of Novel Tetrahydrobenzo[4′,5′]thieno[3′,2′:5,6]pyrido[4,3-d]pyrimidine Derivatives.;ChemInform;2015-01-29