Discovery of 3-hydroxy-3-pyrrolin-2-one-based mPGES-1 inhibitors using a multi-step virtual screening protocol-Reference-Cited by-同舟云学术

Discovery of 3-hydroxy-3-pyrrolin-2-one-based mPGES-1 inhibitors using a multi-step virtual screening protocol

Published:2018 Issue:12 Volume:9 Page:2028-2036
ISSN:2040-2503
Container-title:MedChemComm
language:en
Short-container-title:Med. Chem. Commun.

Author:

Lauro Gianluigi¹²³⁴^ORCID,Cantone Vincenza¹²³⁴,Potenza Marianna¹²³⁴,Fischer Katrin⁵⁶⁷⁸⁹,Koeberle Andreas⁵⁶⁷⁸⁹,Werz Oliver⁵⁶⁷⁸⁹,Riccio Raffaele¹²³⁴,Bifulco Giuseppe¹²³⁴^ORCID

Affiliation:

1. Department of Pharmacy

2. University of Salerno

3. 84084 Fisciano

4. Italy

5. Department of Pharmaceutical/Medicinal Chemistry

6. Institute of Pharmacy

7. Friedrich-Schiller-University Jena

8. D-07743 Jena

9. Germany

Abstract

Virtual screening is a useful tool for disclosing new chemical species able to inhibit mPGES-1.

Funder

Associazione Italiana per la Ricerca sul Cancro

Publisher

Royal Society of Chemistry (RSC)

Subject

Pharmaceutical Science,Biochemistry,Drug Discovery,Molecular Medicine,Pharmacology,Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2018/MD/C8MD00497H

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