Synthesis of pyrrolidin-2-ylidenes and pyrrol-2-ylidenes via 1,3-dipolar cycloaddition of H-bond-assisted azomethine ylides to nitrostyrenes

Author:

Yavari Issa1ORCID,Mohsenzadeh Ramin1,Ravaghi Parisa1,Safaei Maryam1

Affiliation:

1. Department of Chemistry, Tarbiat Modares University, PO Box 14115-175, Tehran, Iran

Abstract

Diastereoselective formation of pyrrolidene-2-ylidenes by the Huisgen reaction of hydrogen-bond-assisted azomethine ylides with β-bromo-β-nitrostyrenes is reported.

Funder

Tarbiat Modares University

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Reference63 articles.

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4. A.Padwa and W. H.Pearson , Synthetic Applications of 1,3-Dipolar Cycloaddition Chemistry Toward Heterocycles and Natural Products , in The Chemistry of Heterocyclic Compounds , Wiley, New York, NY, USA , 2003 , vol. 59

5. N.Nishiwaki , Methods and Applications of Cycloaddition Reactions in Organic Synthesis , Wiley-VCH , Weinheim, Germany , 2014

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