Total synthesis and preliminary SAR study of (±)-merochlorins A and B-Reference-Cited by-同舟云学术

Total synthesis and preliminary SAR study of (±)-merochlorins A and B

Published:2016 Issue:1 Volume:14 Page:198-205
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Yang Hongzhi¹²³⁴⁵,Liu Xue⁶³⁴⁵⁷,Li Qingong¹²³⁴⁵,Li Longbo¹²³⁴⁵,Zhang Jing-Ren⁶³⁴⁵⁷,Tang Yefeng¹²³⁴⁵

Affiliation:

1. The Comprehensive AIDS Research Center

2. and Department of Pharmacology & Pharmaceutical Sciences

3. School of Medicine

4. Tsinghua University

5. Beijing 100084

6. Department of Basic Medical Sciences

7. China

Abstract

A modular synthesis of merochlorins A and B, two naturally occurring antibiotics, has been achieved from the readily available building blocks in a highly concise manner.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/OB/C5OB01946J

Reference37 articles.

1. Recent Advances in the Chemistry and Biology of Naturally Occurring Antibiotics

2. New Targets and Screening Approaches in Antimicrobial Drug Discovery

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5. Platensimycin and its relatives: A recent story in the struggle to develop new naturally derived antibiotics

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