Antibiotic administration in targeted nanoparticles protects the faecal microbiota of mice-Reference-Cited by-同舟云学术

Antibiotic administration in targeted nanoparticles protects the faecal microbiota of mice

Published:2021 Issue:3 Volume:12 Page:380-383
ISSN:2632-8682
Container-title:RSC Medicinal Chemistry
language:en
Short-container-title:RSC Med. Chem.

Author:

Borsa Baris A.¹²³⁴⁵,Sudagidan Mert⁶⁷⁸⁹,Aldag Mehmet E.¹⁰¹¹¹²⁹,Baris Isik I.¹³¹⁴¹⁵⁹,Acar Elif E.⁶⁷⁸⁹,Acuner Cagatay¹⁰¹⁶¹⁷¹⁵⁹,Kavruk Murat¹⁸¹⁹²⁰⁹,Ozalp Veli C.²¹¹⁶²²²³⁹^ORCID

Affiliation:

1. Nucleic Acid Technologies Lab

2. Department of Physics

3. Chemistry and Biology (IFM)

4. Linköping University

5. Linköping

6. Kit-Argem Research Centre

7. Konya Food and Agriculture University

8. Konya

9. Turkey

10. Department of Medical Microbiology

11. Corlu State Hospital

12. Tekirdag

13. Department of Pathology

14. Cakmak Erdem Hospital

15. Istanbul

16. Medical School

17. Yeditepe University

18. Test and Calibration Center

19. Turkish Standards Institution (TSE)

20. Kocaeli

21. Department of Medical Biology

22. Atilim University

23. Ankara

Abstract

Teicoplanin doped and aptamer-gate functionalized mesoporous silica nanoparticles targeted Staphylococcus aureus and reduced the infection load successfully. However, microbiota communities were undisturbed while free teicoplanin caused dysbiosis.

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Drug Discovery,Pharmaceutical Science,Pharmacology,Molecular Medicine,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/MD/D0MD00347F

Reference19 articles.

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