The probiotic Companilactobacillus crustorum MN047 alleviates colitis-associated tumorigenesis via modulating the intestinal microenvironment

Author:

Wang Tao1,Wang Panpan1,Ge Wupeng1ORCID,Shi Chao1ORCID,Xiao Gongnian2,Wang Xin1,Lü Xin1ORCID

Affiliation:

1. College of Food Science and Engineering, Northwest Agriculture and Forestry University, Yangling, Shaanxi 712100, China

2. Zhejiang Provincial Key Lab for Biological and Chemical Processing Technologies of Farm Products, School of Biological and Chemical Engineering, Zhejiang University of Science and Technology, Hangzhou, Zhejiang 310023, China

Abstract

This study investigated the protective effect of C. crustorum MN047 on the AOM/DSS-induced CA-CRC mice, as demonstrated by the amelioration of gut barrier damage, inflammation and regulation of gut microbiota.

Funder

Chinese Universities Scientific Fund

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

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