β-Configured clickable [18F]FDGs as novel 18F-fluoroglycosylation tools for PET-Reference-Cited by-同舟云学术

β-Configured clickable [18F]FDGs as novel 18F-fluoroglycosylation tools for PET

Published:2017 Issue:18 Volume:41 Page:10231-10236
ISSN:1144-0546
Container-title:New Journal of Chemistry
language:en
Short-container-title:New J. Chem.

Author:

Elgland M.¹²³⁴⁵,Nordeman P.⁶⁷⁸⁵,Fyrner T.¹²³⁴⁵,Antoni G.⁶⁷⁸⁵,Nilsson K. Peter R.¹²³⁴⁵^ORCID,Konradsson P.¹²³⁴⁵

Affiliation:

1. Linköpings University

2. IFM – Department of Biology

3. Chemistry & Physics

4. SE-581 83 LINKÖPING

5. Sweden

6. Department of Medicinal Chemistry

7. Uppsala University

8. Uppsala SE-75123

Abstract

We have developed a chemoselective ¹⁸F-fluoroglycosylation method for PET imaging that employ β-configured [¹⁸F]FDGs as prosthetic groups for ¹⁸F-labeling using CuAAC click chemistry.

Funder

Vetenskapsrådet

Swedish Foundation for Strategic Research

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2017/NJ/C7NJ00716G

Reference30 articles.

1. A Broad Overview of Positron Emission Tomography Radiopharmaceuticals and Clinical Applications: What Is New?

2. Carbohydrate-Based Molecules for Molecular Imaging in Nuclear Medicine

3. Metabolic Positron Emission Tomography Imaging in Cancer Detection and Therapy Response

4. Sweetening Pharmaceutical Radiochemistry by18F-Fluoroglycosylation: A Short Review

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