Dual-drug loaded nanoformulation with a galactosamine homing moiety for liver-targeted anticancer therapy
Author:
Affiliation:
1. State Key Laboratory of Coordination Chemistry
2. School of Chemistry and Chemical Engineering
3. Nanjing University
4. Nanjing 210023
5. P. R. China
6. State Key Laboratory of Pharmaceutical Biotechnology
7. School of Life Sciences
Abstract
A platinum(iv) complex was prepared as a prodrug of cisplatin and co-loaded with α-tocopheryl succinate into the galactosamine-modified PLGA nanoparticle for combinational chemotherapy of liver cancer.
Publisher
Royal Society of Chemistry (RSC)
Subject
Inorganic Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2016/DT/C6DT01434H
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