Synthesis of protected 2′-O-deoxyribonucleotides on a precipitative soluble support: a useful procedure for the preparation of trimer phosphoramidites-Reference-Cited by-同舟云学术

Synthesis of protected 2′-O-deoxyribonucleotides on a precipitative soluble support: a useful procedure for the preparation of trimer phosphoramidites

Published:2016 Issue:107 Volume:6 Page:105428-105432
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Kungurtsev V.¹²³⁴,Lönnberg H.¹²³⁴,Virta P.¹²³⁴

Affiliation:

1. Department of Chemistry

2. University of Turku

3. FI-20014 Turku

4. Finland

Abstract

A straightforward procedure for the preparation of protected 2′-O-deoxyribonucleotide trimers, using the phosphotriester chemistry on a precipitative soluble support, was described.

Funder

Suomen Akatemia

Seventh Framework Programme

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/RA/C6RA22316H

Reference21 articles.

1. A general strategy for random insertion and substitution mutagenesis: substoichiometric coupling of trinucleotide phosphoramidites.

2. Chemical and biochemical strategies for the randomization of protein encoding DNA sequences: library construction methods for directed evolution